Overview
The AELAB ZRS-6ST Dissolution Tester is used to examine the dissolving speed and degree of solid preparations such as drug tablets or capsules in specified solvents. The instrument adopts a classical modeling design and delivers high performance, stability, reliability, simple operation, and long-term durability.
ZRS-6ST is a new-generation drug dissolution tester developed and produced by our company. It features an electric lifting head with overturn capability, allowing convenient paddle and basket replacement. All working parameters can be preset and stored automatically for repeatable workflows.
⚙️ Design & Construction
The AELAB ZRS-6ST is engineered with a stainless steel paddle rod, basket rod, and basket turning components that comply with Chinese Pharmacopoeia quality requirements. The system incorporates an electric lifting mechanism enabling automatic head raise and overturn for improved access during method setup. A thermostatic water bath with integrated temperature sensor ensures stable and uniform heating across all six dissolution cups. The large LCD interface provides clear visualization of operating status and parameter settings.
🔬 Working Principle / Testing Method
The dissolution process in the ZRS-6ST operates by rotating paddles or baskets at a controlled speed between 20–200 rpm while maintaining the water bath at a precise temperature up to 45℃. The electronic sensor continuously monitors temperature across multiple bath points. Sampling periods are programmable from 1–999 minutes, with up to nine intervals available for automatic countdown. Pharmacopoeia test methods can be recalled directly, enhancing compliance and reducing setup time.
💡 Key Advantages
- Electric head lift and automatic overturn mechanism for rapid paddle or basket changeover.
- Stable temperature control with 0.1℃ resolution and ≤±0.3℃ accuracy.
- 20–200 rpm stirring range supporting diverse dissolution protocols.
- Integrated storage of 300 Pharmacopoeia method parameters.
- Electronic multi-point bath temperature monitoring for improved thermal uniformity.
- Preset sampling periods for automated timing and reduced operator intervention.
- LCD interface with intelligent menu for streamlined test configuration.
🔗 Connectivity & Integration
The ZRS-6ST supports digital data export and integrates with external PC software for test record management, GLP reporting, and method documentation. Operation logs, temperature data, and sampling timestamps can be stored and reviewed to support audit and compliance processes.
🧠 Model Insight
The ZRS-6ST represents the single-model configuration within its category. Key operational parameters are summarized below:
| Model |
Specifications |
| ZRS-6ST |
6-cup dissolution system, 20–200 rpm, ≤±0.3℃ temperature accuracy, 1100W heating power |
🧪 Testing Applications
The AELAB ZRS-6ST is used for pharmaceutical development, QC laboratories, academic research, and regulatory testing. It supports dissolution analysis of immediate-release tablets, capsules, coated products, and solid dosage forms. The system is suitable for formulators, manufacturers, and laboratories performing method validation and routine batch verification.
Compliance & Quality Assurance
The dissolution tester meets Chinese Pharmacopoeia requirements and follows ISO- and GLP-aligned quality control standards. All components undergo rigorous calibration and stability testing to ensure consistent analytical performance.